Working out structure of proteins has been a long drawn process for structural Bioinformaticians. PyMod is an attempt to integrate some of the commonly used tools like BLAST, HMMER, Clustal, MUSCLE, PSIPRED, DOPE and MODELLER with molecular graphic viewer PyMOL.
It has a graphical user interface and has been written in PyQt. Starting from an amino acid sequence users can build structures of proteins using homology modelling. PyMod3 can also perform sequence similarity searches, multiple sequence/structure alignment building, phylogenetic trees and evolutionary conservation analyses, domain parsing, single/multiple chains and loop modeling.
The package is available at https://github.com/pymodproject/pymod.
Refrence:
Janson G. et. al.(2021) PyMod 3: a complete suite for structural bioinformatics in PyMOL. Bioinformatics 37(10) : 1471-1472.